Enzyme links metabolic state to inflammatory response to infection
Jul 26, 2016
An enzyme that stimulates the breakdown of fats in immune cells helps trigger inflammation, or an immune response to pathogens, a new study by Weill Cornell Medicine researchers suggests. The findings enhance scientists' ...
DNA-modulating drug attenuates lung inflammation in mice
Jul 21, 2016
Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have suggested that a specific ...
Stop the rogue ADAM gene and you stop asthma
Jul 21, 2016
Scientists at the University of Southampton have discovered a potential and novel way of preventing asthma at the origin of the disease, a finding that could challenge the current understanding of the condition.
Fracking industry wells associated with increased risk of asthma attacks, study finds
Jul 18, 2016
People with asthma who live near bigger or larger numbers of active unconventional natural gas wells operated by the fracking industry in Pennsylvania are 1.5 to four times likelier to have asthma attacks than those who live ...
Do kids grow out of childhood asthma?
Jul 18, 2016
When a child is diagnosed with asthma, parents usually have a number of questions. How serious is asthma? Will the child grow out of it? How can it be treated? It can be difficult to get clear answers, as asthma affects different ...
Increase in childhood and adult asthma linked to London's 1952 Great Smog
Jul 08, 2016
London's Great Smog of 1952 resulted in thousands of premature deaths and even more people becoming ill. The five December days the smog lasted may have also resulted in thousands more cases of childhood and adult asthma. ...
Natural metabolite can suppress inflammation
Jul 01, 2016
An international group of scientists from the U.S., Canada, Germany and Russia has revealed a naturally occurring organic compound that can suppress the pro-inflammatory activity of macrophages. The compound, itaconate, is ...
Enhanced arginine metabolism may counteract inflammation pathways in asthma
May 23, 2016
High arginine levels are often observed in asthmatic individuals and may support increased production of nitric oxide, which is known to worsen airway inflammation. Medications that reduce arginine availability do not effectively ...
Strategy for depleting immune cells implicated in asthma-associated inflammation
May 19, 2016
Patients with asthma have chronic lung inflammation that results in sporadic narrowing of the airways and difficulty breathing. Symptoms and severity are variable among individuals; however, the cells and inflammatory factors ...
Novel gene therapy shows potential for lung repair in asthma
May 18, 2016
A new study has demonstrated a way to deliver a nanoparticle-based gene therapy, in order to repair lungs damaged by chronic allergic asthma and to reduce inflammation that causes asthma attacks. The potential therapy, tested ...