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Medications

Targeting specific protein regions offers a new treatment approach in medulloblastoma

Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...

Medications

Study: Antibiotic use in patients hospitalized with COVID-19 appears to have no beneficial effect on clinical outcomes

Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ...

Medications

Treatment for deadly superbug C. diff may be weakening

The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston ...

Medications

A closed-loop drug-delivery system could improve chemotherapy

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that ...

Medications

Study finds AI can develop treatments to prevent 'superbugs'

Cleveland Clinic researchers developed an artificial intelligence (AI) model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the ...

Medications

Use of acid reflux drugs linked to higher risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology ...

Medications

Follow-up finds landmark steroid study remains safe 50 years on

A study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given corticosteroids because they were at risk of early birth in a landmark trial conducted ...

Medications

Are probiotics all they're cracked up to be?

Probiotics have been touted as a treatment for everything from diarrhea to mental health disorders, with sales of probiotic supplements expected to exceed $65 billion globally in 2024.

Medications

New drug may slow rapid progression of Parkinson's disease

Prasinezumab, a monoclonal antibody, is shown to reduce signs of motor deterioration in individuals with Parkinson's disease (PD) who have rapidly progressing disease, as reported in an exploratory analysis of data from a ...

Medications

Common HIV treatments may aid Alzheimer's disease patients

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...

Medications

Combination therapy can delay resistance of lung cancer cells

A specific genetic alteration, known as an ALK fusion, drives non-small cell lung cancer in some patients. This abnormality leads to excessive activity of the ALK protein, a key cancer promoter. These tumors can be treated ...

Medications

Penicillin allergy can be delabeled by nonallergy providers

Direct oral penicillin challenges (DPCs) can be delivered to patients with penicillin allergy labels (PALs) by nonallergy health care professionals (HCPs), according to a study published in the March issue of the Journal ...