Closer look at proteins involved in Parkinson's disease reveals segment involved in amyloid formation
Sep 10, 2015 report
(Medical Xpress)—A team of scientists from several research centers in the U.S. has taken a closer look at α-synuclein, a protein that is abundant in the human brain, and which is also involved in the development of Parkinson's ...
Major complication of Parkinson's therapy explained
Sep 10, 2015
Researchers have discovered why long-term use of L-DOPA (levodopa), the most effective treatment for Parkinson's disease, commonly leads to a movement problem called dyskinesia, a side effect that can be as debilitating as ...
Parkinson's disease brain cells at risk of burnout, like an overheating motor
Aug 27, 2015
The death of brain cells in Parkinson's disease may be caused by a form of cellular energy crisis in neurons that require unusually high quantities of energy to carry out their job of regulating movement, researchers at the ...
New research sheds light on the molecular origins of Parkinson's disease
Aug 10, 2015
As Parkinson's disease progresses in patients, a puzzling dichotomy plays out in their brains. One set of neurons degenerates, while a similar population nearby is spared the same degree of damage. Why the difference? An ...
Single protein causes Parkinson's disease and multiple system atrophy
Jun 10, 2015
Several neurodegenerative disorders are caused by aggregates of a single protein known as alpha-synuclein. In collaboration with CNRS and the University of Antwerp, KU Leuven neurobiologists have discovered that the shape ...
Unraveling the mystery of a-synuclein in neurodegenerative disease and reversing its course
May 12, 2015
A team of neuroscientists at Georgetown University Medical Center has shown how a protein, known to accumulate in Parkinson's disease and other neurodegenerative diseases, activates the brain's immune response.
Study identifies key factor in neural death that causes Parkinson's disease
Apr 28, 2015
In studying the molecular biology of brain development, a team of researchers led by Ludwig Stockholm director Thomas Perlmann has discovered how disruption of a developmental mechanism alters the very nerve cells that are ...
Mitochondria are altered in human cell model of Parkinson's disease
Apr 02, 2015
Based on research in fruit flies, it has long been suspected that the most common mutation linked to both sporadic and familial Parkinson's disease (PD) wreaks its havoc by altering the function of mitochondria in neurons ...
By revealing loss of motor skills, typing patterns may help to identify early onset of Parkinson's
Apr 02, 2015
Analyzing people's keystrokes as they type on a computer keyboard can reveal a great deal of information about the state of their motor function, according to a new study from MIT.
Tackling Parkinson's with targeted therapeutic vaccines
Dec 24, 2014
Clinical trials are about to begin on a new Parkinson's disease vaccine that could offer patients significant improvements over current treatments. The vaccine, developed through the FP7-funded SYMPATH project, may actually ...