Diseases, Conditions, Syndromes

Common cold virus linked to potentially fatal blood clotting disorder

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop ...

Diseases, Conditions, Syndromes

Investigating acute hepatitis of unknown origin in children

Since Fall 2021, an increasing number of unexplained cases of severe acute hepatitis have been reported in children. Epidemiologic investigation is ongoing, and, to date, a cause of these outbreaks has not been identified. ...

Diseases, Conditions, Syndromes

Why the mystery hepatitis in children may have been here all along

The children typically show up at hospitals scattered across the country, one or two at a time, with symptoms like unexplained vomiting, diarrhea and jaundice. These are the classic signs of hepatitis—inflammation of the ...

Vaccination

WHO clears China's CanSino COVID vaccine for emergency use

The World Health Organization said Thursday that it has granted an emergency use authorization for the coronavirus vaccine made by China's CanSino Biologics, the 11th such shot to receive the green light.

Diseases, Conditions, Syndromes

What may be behind the unexplained cases of hepatitis in kids?

Several countries, including the U.S., have identified or are investigating unexplained hepatitis cases in children. While the reported cases are appearing in clusters, they remain rare. About 200 children are affected worldwide.

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Adenoviridae

Adenoviruses are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are 57 described serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well.

Viruses of the family Adenoviridae infect various species of vertebrates, including humans. Adenoviruses were first isolated in 1953 from human adenoids. They are classified as group I under the Baltimore classification scheme, meaning their genomes consist of double stranded DNA.

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