Diseases, Conditions, Syndromes

Investigating the pathogenesis of rare congenital nerve disorder

A new Northwestern Medicine study has uncovered previously unidentified intracellular mechanisms in the peripheral nervous system that cause Charcot–Marie–Tooth Type 2B disease, a rare congenital disorder that causes ...

Medical research

Neurology: Early treatment is half the battle

Neurological diseases often begin with an inflammatory process and the degradation of the myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer. This is usually followed by damage to the ...

Neuroscience

Perilous ruptures described in a multiple sclerosis model

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ...

Neuroscience

Study identifies new target to preserve nerve function

Scientists in the Vollum Institute at OHSU have identified an enzyme that plays a crucial role in the degeneration of axons, the threadlike portions of a nerve cell that transmit signals within the nervous system. Axon loss ...

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