Aging (senescent) cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.
Mar 30, 2023
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231
An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health ...
Nov 14, 2022
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45
People with HIV who have moderate immune suppression appear to be at greater risk of severe COVID-19 "breakthrough" infection after vaccination, according to a study led by researchers at the Johns Hopkins Bloomberg School ...
Oct 13, 2022
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46
Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) have identified how to increase the ability of tissue-resident memory T (TRM) cells to help fight viral infections and certain cancers.
Jul 27, 2022
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62
How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus, or both are providing tantalizing ...
May 19, 2022
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67
Tumor-infiltrating lymphocytes (TILs) play a key role in the antitumor immune response and various types of immunotherapies. Recently, studies have shown that CD4+ T cells and CD8+ T cells are equally important for an efficient ...
May 12, 2022
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4
Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such pathogens pose significant ...
Apr 8, 2022
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Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of ...
Mar 23, 2022
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138
Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. ...
Feb 3, 2022
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124
Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells—the heavy armor of the immune system—according to a study from researchers ...
Aug 16, 2021
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CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene.
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