Oncology & Cancer

Identifying the inflammatory cells behind chemo brain

Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice ...

Medical research

Technique targets cancer cells and leaves healthy ones alone

It is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, followed by hopes that chemotherapy will save the day. Unfortunately, for many patients, chemo's painful side effects cause ...

Oncology & Cancer

Researchers ID risks for second childhood cancers

Chemotherapy and radiation treatments have helped children survive cancer. Now University of Minnesota researchers are trying to find the ideal combinations that prevent the disease from coming back.

Oncology & Cancer

A possible gut-brain connection to 'chemo brain'

Scientists looking for evidence of the gut's involvement in cognitive and mood problems related to chemotherapy treatment are testing their theories with the help of an unsavory rodent habit: eating feces.

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Chemotherapy

Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen.

Most commonly, chemotherapy acts by killing cells that divide rapidly, one of the main properties of most cancer cells. This means that it also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract and hair follicles. This results in the most common side effects of chemotherapy: myelosuppression (decreased production of blood cells, hence also immunosuppression), mucositis (inflammation of the lining of the digestive tract), and alopecia (hair loss).

Newer anticancer drugs act directly against abnormal proteins in cancer cells; this is termed targeted therapy and is technically not chemotherapy.

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