What role do omega-6 fatty acids play in cardiovascular disease and diabetes? Scientists from Mannheim, together with researchers from Heidelberg, Frankfurt, and Hangzhou in China, have investigated the breakdown of omega-6 ...
Dec 21, 2023
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For patients with newly diagnosed multiple myeloma (NDMM), a nomogram based on the inflammatory-nutritional score (INS) may help to predict survival, according to a study published online Jan. 5 in the Journal of Inflammation ...
Jan 20, 2023
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Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...
Aug 16, 2022
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A team of investigators has discovered that the underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma (ccRCC), according to a recent study ...
Oct 21, 2021
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For decades, scientists and doctors have been searching for a cure for cancer. Now, researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have taken a significant ...
Nov 16, 2020
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A common mutation in a key enzyme involved in alcohol metabolism increases damage in cells from patients with Alzheimer's disease and in mice, according to a study by researchers at the Stanford University School of Medicine.
Dec 11, 2019
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If your face goes red when drinking alcohol, you're not alone. More than one in three people with East Asian heritage (Chinese, Japanese and Korean) experience facial flushing when drinking beer, wine or spirits.
Dec 28, 2017
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Researchers used gene transfer to block the expression of one of the two main enzymes that break down alcohol in the liver, leading to the accumulation in liver cells of acetaldehyde, a metabolic byproduct of ethanol. The ...
Sep 18, 2017
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People who have reduced enzyme activity to breakdown active aldehyde, i.e., those who become easily inebriated, are more likely to develop fatty liver disease even if they do not drink alcohol. This discovery was made by ...
May 24, 2016
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In cardiac hypertrophy, metabolic energy reserves in the heart are depleted, which is thought to contribute to the subsequent development of heart failure. The primary energy source in the heart relies on fatty acid oxidation ...
Feb 25, 2016
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