Medical research

Possible treatment on the horizon for severe dengue disease

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. ...

Diseases, Conditions, Syndromes

Zika may hijack mother-fetus immunity route

To cross the placenta, Zika virus may hijack the route by which acquired immunity is transferred from mother to fetus, new research suggests.

Diseases, Conditions, Syndromes

Philippines says deaths in vaccine row 'consistent with' dengue

The Philippines said Thursday that some of the 14 children who died after receiving a controversial vaccine showed signs of "severe dengue", as investigators probe the drug whose use was suspended due to health concerns.

Diseases, Conditions, Syndromes

Do mast cells contribute to more severe disease in dengue infection?

Why mosquito-borne dengue virus causes more severe disease in some individuals, including hemorrhagic fever with or without shock, remains controversial and researchers are focusing on the factors related to the interaction ...

Diseases, Conditions, Syndromes

Blood test predicts kids at risk for dengue shock syndrome

The most serious, life-threatening complication of dengue infection is dengue shock syndrome (DSS), seen primarily in children. Daily platelet counts in children in the early stages of dengue can predict those most at risk ...

Diseases, Conditions, Syndromes

Dengue protein modulates human enzyme: Fuel for replication

Dengue is a mosquito-borne tropical disease currently endemic in more than 10 countries. According to the World Health Organization, 390 million people are infected by dengue every year.

Diseases, Conditions, Syndromes

Scientists close in on first dengue treatment

Clinical trials for a dengue fever treatment could start within a year, following a discovery by University of Queensland scientists.

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