Safety concerns related to the widely used painkiller diclofenac may be tied to a little-studied drug-metabolizing enzyme whose expression can vary as much as 3,000 times from one individual to the next, according to new ...
Apr 24, 2023
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Diclofenac and other non‐steroidal anti‐inflammatory drugs (NSAIDs) may limit the passage of gamma hydroxybutyric acid (a narcolepsy medication and illicit party drug commonly known as GHB) to the brain, decreasing the ...
Aug 23, 2021
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Once damaged, the human heart does a poor job of repairing itself, and is thus a key priority for treating heart failure. One way of restoring cardiac function is to reprogram non-cardiac body cells such as fibroblasts into ...
Mar 6, 2019
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(HealthDay)—Diclofenac initiators have increased cardiovascular risk compared with non-initiators, according to a study published online Sept. 4 in The BMJ.
Oct 1, 2018
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The commonly used painkiller diclofenac is associated with an increased risk of major cardiovascular events, such as heart attack and stroke, compared with no use, paracetamol use, and use of other traditional painkillers, ...
Sep 4, 2018
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Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.
Jan 11, 2016
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(HealthDay)—Use of specific nonsteroidal anti-inflammatory drugs (NSAIDs), diclofenac and aceclofenac, is associated with increased risk of nonfatal ischemic stroke, according to a study published online Jan. 22 in the ...
Feb 12, 2015
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(HealthDay)—For patients undergoing photorefractive keratectomy surgery, the administration of postoperative topical diclofenac does not alleviate pain, but is effective for local signs such as eyelid edema, according to ...
Jan 9, 2015
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Women who take nonsteroidal anti-inflammatory drugs (NSAIDs) during pregnancy are not at increased risk of miscarriages, confirms a new study published in CMAJ (Canadian Medical Association Journal).
Feb 3, 2014
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The increased risk of heart attack or stroke associated with many arthritis drugs may be avoidable, according to a new international study co-authored by researchers at Imperial College London.
Jul 4, 2013
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Diclofenac (marketed under many brand names, see below: Trade names) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
The name is derived from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid.
In the United Kingdom, India, Brazil and the United States, it may be supplied as either the sodium or potassium salt, in China most often as the sodium salt, while in some other countries only as the potassium salt. Diclofenac is available as a generic drug in a number of formulations. Over-the-counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.
This text uses material from Wikipedia, licensed under CC BY-SA
