A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis ...
Jan 2, 2024
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A new research paper titled "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair" has been published in Oncotarget.
Jun 12, 2023
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27
Hunting for disease clues in the dark matter of our DNA, scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes ...
Jan 18, 2023
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Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering ...
Aug 23, 2022
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Some physical traits that differ between sexes are known to be linked to certain single nucleotide polymorphisms (SNPs) in chromosomes other than the X and Y chromosomes, with each SNP representing a difference in a certain ...
May 5, 2022
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Over time, we accumulate genetic damage that accelerates the aging process, increasing the risk of carcinogenesis. DNA is continually challenged by genotoxic factors that affect its fragile structure, inhibiting cell functions. ...
Jun 1, 2021
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The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search for effective cures. ...
Feb 16, 2021
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Today's DNA testing is highly accurate, but errors still occur due to the limited genetic information accessible with current technologies. These errors can have serious impact on people's lives.
Aug 18, 2020
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14
Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. Offering a new perspective ...
Oct 8, 2019
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3
We all have tiny, protein-operated clocks inside our cells that operate based upon the 24-hour day cycle. These circadian clocks are important for the proper biological function of different organs - heart, liver, lungs, ...
May 7, 2018
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