Medications
GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study
A new research paper titled "GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells" has been published in Oncotarget.
Feb 27, 2024
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News tagged with er stress
Neuroscience
A promising drug candidate for ALS prolongs lifespan and eases symptoms in rats and mice
A research group at the University of Helsinki and its partners have found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan ...
Sep 22, 2023
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Medical research
Following chronic fatigue mechanisms to the source: WASF3 and mitochondrial respiration
Researchers at the National Heart, Lung, and Blood Institute at NIH, Bethesda, have discovered a potential breakthrough for people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), marked by extreme exhaustion, ...
Medical research
SLFN11's surveillance role in protein homeostasis
A new research perspective published in Oncoscienceexplores SLFN11's surveillance role in protein homeostasis.
Aug 3, 2022
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Medical research
Cell stress mechanisms identified as prognostic factor for chronic inflammatory liver disease
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research ...
Mar 30, 2021
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Oncology & Cancer
Eating less suppresses liver cancer due to fatty liver
Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan. In order to change this unfortunate state of affairs, it is important to improve the prognosis of non-alcoholic ...
Oct 29, 2020
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Medical research
Improved understanding of the pathology of dwarfism may lead to new treatment targets
Pseudoachondroplasia (PSACH) is a severe inherited dwarfing condition characterized by disproportionate short stature, joint laxity, pain, and early onset osteoarthritis. In PSACH, a genetic mutation leads to abnormal retention ...
Dec 12, 2018
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Oncology & Cancer
New therapeutic strategy for treating a very aggressive form of breast cancer
Scientists have identified a new therapeutic strategy for treating a very aggressive form of breast cancer.
Oct 15, 2018
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Medical research
Major step found in cellular response to stress caused by pathological insult
A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond ...
Mar 6, 2018
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Diabetes
Cellular calcium handling in diabetes
Tight regulation of calcium levels in the endoplasmic reticulum (ER) – a cellular organelle with multiple functions – contributes to insulin secretion by pancreatic beta cells. Although ER calcium handling is perturbed ...
Sep 29, 2017
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