Medical research

Exercise rescues mutated neural stem cells

CHARGE syndrome is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the ...

Medical research

Scientists discern signatures of old versus young stem cells

A chemical code scrawled on histones—the protein husks that coat DNA in every animal or plant cell—determines which genes in that cell are turned on and which are turned off. Now, Stanford University School of Medicine ...

Genetics

Researchers identify another piece of the 'histone code' puzzle

(Medical Xpress)—DNA is often called the blueprint of life, but the four-letter combinations that make up the genetic code are just part of the story. Built upon the DNA lies additional epigenetic information in the form ...

Genetics

Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

Medical research

Influenza 'histone mimic' suppresses antiviral response

(Medical Xpress) -- For a virus like influenza, the key to success isn't in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at The Rockefeller University has identified a ...