The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...
Mar 10, 2023
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24
A newly constructed map of the landscape of genetic changes in chronic lymphocytic leukemia (CLL), a type of cancer of the blood and bone marrow that exists in diverse forms and arises from various causes, provides a better ...
Aug 4, 2022
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53
One way in which the body combats COVID-19 is by mutating the coronavirus, making it less harmful. This built-in protective mechanism in cells has a clear connection with decreased viral load in the body, a study from the ...
Feb 9, 2022
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350
In an unprecedented pan-cancer analysis of whole genomes, researchers at the Ontario Institute for Cancer Research (OICR) have discovered new regions of non-coding DNA that, when altered, may lead to cancer growth and progression.
Jan 18, 2020
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135
Scientists have devised a new computational method that reveals genetic patterns in the massive jumble of individual cells in the body.
Aug 1, 2019
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Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather, the location of DNA mutations is relevant. Using ...
Nov 29, 2018
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Sleep is vital for adequate functioning across the animal kingdom, but little is known about the physiological mechanisms that regulate it, or the reasons for natural variation in people's sleep patterns.
Sep 24, 2018
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16
A team of researchers affiliated with several institutions in the U.K. and one in the U.S. has developed a way to use artificial intelligence to predict how cancer might change and spread in patients. The results are published ...
A new statistical model developed by a research team at Worcester Polytechnic Institute (WPI) may enable physicians to create personalized cancer treatments for patients based on the specific genetic mutations found in their ...
Dec 11, 2014
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Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...
May 31, 2013
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