Medical research

Toxoplasma gondii parasite may alter signaling in the brain

It's creepy, it's crawly, and it infects 20 percent of people in the United States. Fortunately, most people who carry the Toxoplasma gondii parasite don't develop the symptoms of the disease it can cause. Only a small fraction ...

Medical research

Scientists identify principal protein sensor for touch

A team led by biologists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in neuroscience by identifying the "mechanoreceptor" protein that mediates the sense of touch in mammals.

Neuroscience

Neurons can use local stores for communication needs

Researchers reveal that neurons can utilize a supremely localized internal store of calcium to initiate the secretion of neuropeptides, one class of signaling molecules through which neurons communicate with each other and ...

Parkinson's & Movement disorders

Shedding light on early Parkinson's disease pathology

In a mouse model of early Parkinson's disease (PD), animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), ...

Addiction

Study examines effects of Ibudilast and metamphetamines

John W. Tsuang, M.D., principal investigator at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), in conjunction with Steven J. Shoptaw, Ph.D., from the UCLA Department of Family Medicine, ...

Psychology & Psychiatry

GABA deficits disturb endocannabinoid system

Changes in the endocannabinoid system may have important implications for psychiatric and addiction disorders. This brain system is responsible for making substances that have effects on brain function which resemble those ...