A healthier diet is associated with serum metabolite concentrations indicative of better cardiovascular health already in school-aged children, a recent study from the University of Eastern Finland shows. Published in the ...
Jan 15, 2024
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The analysis of all small molecules in an organism (the metabolome) has huge potential for medical diagnostics. A German research team is investigating this with nuclear magnetic resonance spectrometry (NMR).
Jul 24, 2023
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More than 70 FDA-approved cancer drugs are kinase inhibitors, which work by blocking kinases—enzymes that add phosphate groups to molecules in the cell—and preventing the chemical activity necessary for signaling and ...
Feb 13, 2023
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Researchers have worked out how to successfully switch off a key pathway of nerve fiber breakdown in debilitating neurodegenerative disorders such as Parkinson's disease, traumatic brain injury and glaucoma.
Mar 28, 2022
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Cancer is a group of diseases involving abnormal cell growth with the potential to spread throughout the body. About 19.3 million new cancer cases and 10 million cancer-related deaths were reported worldwide in 2020. More ...
Jan 26, 2021
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Scientists at St. Jude Children's Research Hospital have visualized previously unknown structures of the ABL kinase, offering insight for designing the next generation of targeted therapies for adult and childhood cancers. ...
Oct 2, 2020
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A team of scientists from the Moscow Institute of Physics and Technology (MIPT) and Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (IBCh RAS) studied one hereditary genetic mutation to discover general molecular ...
Aug 23, 2019
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St. Jude Children's Research Hospital structural biologists have deciphered how the structure of the enzyme called Abl regulates its activity, enabling the enzyme to switch itself on and off. Understanding Abl's regulation ...
Sep 26, 2017
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Using solid-state nuclear magnetic resonance (NMR) spectroscopy, researchers at Luleå University of Technology in collaboration with Warwick University in the UK for the first time in the world managed to analyse hydrogen ...
Nov 5, 2012
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Chemical screening technologies will help doctors to monitor surgical patients before, during and after operations, providing better targeted care and treatment, say Imperial College London experts in an article published ...
May 18, 2011
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