Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss
A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.
Sep 27, 2023
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A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.
Sep 27, 2023
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Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...
Jan 5, 2023
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Significant improvement in progression free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which ...
Sep 12, 2022
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When a muscle grows, because its owner is still growing too or has started exercising regularly, some of the stem cells in this muscle develop into new muscle cells. The same thing happens when an injured muscle starts to ...
Feb 26, 2021
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When a muscle grows or a muscle injury heals, some stem cells develop into new muscle cells. A research team at the MDC led by Carmen Birchmeier has now described in the journal Genes & Development how this process is regulated ...
Mar 18, 2019
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Natural killer cells (NK cells), play an important role in the body's defences against cancer and infections. Now, in a joint project, researchers at Lund University in Sweden, the University of Oxford, and Karolinska Institutet ...
Dec 14, 2018
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Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed. The ...
May 16, 2018
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Investigators at Vanderbilt-Ingram Cancer Center (VICC) and the Virginia Tech Carilion Research Institute (VTCRI) have revealed a gene mutation's role in Von Hippel-Lindau syndrome, a genetically inherited disease which causes ...
Mar 12, 2018
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EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The molecule is a ray of hope for the ...
Sep 1, 2017
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Rafal Ciosk and his group at the FMI have identified an important link between the Notch signaling pathway and PRC2-mediated gene silencing. They showed that a fine balance between epigenetic silencing and signaling is crucial ...
Sep 23, 2016
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