Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Drugs that target opioid receptors sometimes have severe side effects. An international team of researchers has taken a ...
Apr 12, 2024
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Scripps Research scientists have found that LY2444296—a compound that selectively blocks the kappa opioid receptor (KOP)—may reduce drinking in cases of alcohol dependence in animal studies. The findings, which were published ...
Mar 29, 2024
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The herbal substance kratom, derived from the leaves of a Southeast Asian tree, is used by nearly 2 million people in the United States annually. It can be easily purchased at gas stations and convenience stores, smoke shops ...
Feb 21, 2024
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Ketamine, increasingly popular as a treatment for depression and pain, is often prescribed as an alternative to addictive opioids. But the data has been mixed on whether ketamine's effects rely on similar brain pathways as ...
Feb 12, 2024
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A new approach to treating neuropathic pain is making a key step forward thanks to researchers at The University of Texas at Austin.
Jan 30, 2024
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Opioids such as morphine are the gold standard for treating cancer-induced bone pain, but new University of Arizona Health Sciences research published in the journal Pain uncovers a mechanism by which chronic morphine use ...
Jul 6, 2023
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In the United States, federal legislation mandates that all states track data on all newborns who have been exposed to substances during pregnancy and ensure that a plan of Safe Care is created for each family. Yet each state ...
May 31, 2023
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Opioid drugs such as morphine and fentanyl are like the two-faced Roman god Janus: The kindly face delivers pain relief to millions of sufferers, while the grim face drives an opioid abuse and overdose crisis that claimed ...
May 31, 2023
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Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. For decades, scientists have attempted to develop drugs that selectively activate one type of opioid receptor ...
May 3, 2023
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The human body naturally produces opioid-like substances, such as endorphins, that block the perception of pain and increase the feeling of well-being. Similarly, opioid drugs, including morphine or fentanyl, are widely used ...
Apr 19, 2023
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