The development of therapeutic drugs for inflammatory bowel disease, an intractable immune disease, and multiple sclerosis—an autoimmune disorder—is gaining traction. A research team from the Department of Life Sciences ...
Jun 25, 2021
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Type 1 diabetes mellitus and type 2 diabetes mellitus (T2DM) are the two main types of diabetes, while T2DM accounts for 90%-95% of those with diabetes. T2DM is a vital risk factor for cerebral infarction, cardiovascular ...
Jul 13, 2020
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Changes in the gut microbiome have long been linked with Crohn's disease and other forms of inflammatory bowel disease (IBD), but the biology behind those links has remained murky. Researchers at the Broad Institute, Massachusetts ...
Jun 11, 2019
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New research led by the University of Sheffield has discovered how a hospital superbug evades the immune system to cause infection – paving the way for new treatments.
May 2, 2019
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Biomedical scientists at the University of Salford found that sugars from the common cockle (Cerastoderma edule) were approximately as effective as some standard chemotherapy drugs at relative lower dosage.
Sep 17, 2018
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In a study published by JAMA, Jacquelyn M. Powers, M.D., M.S., of the Baylor College of Medicine, Houston, and colleagues compared two medications, ferrous sulfate and iron polysaccharide complex, for the treatment of nutritional ...
Jun 13, 2017
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In several clinical trials, the probiotic bacterium Lactobacillus paracasei DG has been shown to promote health, but until now, the mechanism has remained a black box. New research now suggests that the health benefits arise ...
Dec 2, 2016
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A study revealed today at The International Liver Congress 2015 has demonstrated that alginate-enriched bread has the potential to inhibit fat digestion and circulatory lipids in patients with non-alcoholic fatty liver disease ...
Apr 23, 2015
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Drugs comprised of single strands of DNA, called aptamers, can bind to targets inside tumor cells causing cell death. But these DNA drugs cannot readily get inside tumor cells on their own. Effective delivery of DNA aptamers ...
Jan 27, 2014
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The bacterium Pseudomonas aeruginosa needs iron to establish and maintain a biofilm in the lungs of cystic fibrosis patients, and therapies have been proposed to deprive the bacteria of this necessary element. However, these ...
Aug 20, 2013
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Polysaccharides are long carbohydrate molecules, of repeated monomer units joined together by glycosidic bonds. They range in structure from linear to highly branched. Polysaccharides are often quite heterogeneous, containing slight modifications of the repeating unit. Depending on the structure, these macromolecules can have distinct properties from their monosaccharide building blocks. They may be amorphous or even insoluble in water.
When all the monosaccharides in a polysaccharide are the same type, the polysaccharide is called a homopolysaccharide or homoglycan, but when more than one type of monosaccharide is present they are called heteropolysaccharides or heteroglycans.
Examples include storage polysaccharides such as starch and glycogen, and structural polysaccharides such as cellulose and chitin.
Polysaccharides have a general formula of Cx(H2O)y where x is usually a large number between 200 and 2500. Considering that the repeating units in the polymer backbone are often six-carbon monosaccharides, the general formula can also be represented as (C6H10O5)n where 40≤n≤3000.
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