Medical research

Changing what heart cells eat could help them regenerate

Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die, a new study led by UT Southwestern researchers suggests. The finding, published in the Feb. 20, 2020, Nature ...

Medical research

Deciphering the regenerative potential of newborn mammalian hearts

Unlike lower vertebrates, mammals are unable to repair their adult hearts after injuries that include heart attacks. This inability in humans leads to heart failure—a deadly and costly disease that affects more than 5 million ...

Cardiology

Neonatal pig hearts can heal from heart attack

While pigs still cannot fly, researchers have discovered that the hearts of newborn piglets do have one remarkable ability. They can almost completely heal themselves after experimental heart attacks.

Medical research

Reactivation of embryonic genes leads to muscle aging

Developmental genes and pathways strictly regulate embryogenesis. The process is strongly driven by so-called Hox-genes. Now, researchers from the Leibniz Institute on Aging (FLI) in Jena, Germany, can show that one of these ...

Medical research

Mouse study links heart regeneration to telomere length

Researchers at the Spanish National Center for Cardiovascular Research have discovered that the ends of heart muscle cell chromosomes rapidly erode after birth, limiting the cells' ability to proliferate and replace damaged ...

Medical research

A vitamin that stops the aging process of organs

Nicotinamide riboside (NR) is pretty amazing. It has already been shown in several studies to be effective in boosting metabolism. And now a team of researchers at EPFL's Laboratory of Integrated Systems Physiology (LISP), ...

Oncology & Cancer

Mini-breast grown in Petri dishes—a new tool for cancer research

The research group, led by Dr. Christina Scheel, developed an assay whereby cultured human breast epithelial cells rebuild the three-dimensional tissue architecture of the mammary gland. For this purpose, a transparent gel ...

Medical research

Protein may improve liver regeneration

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα ...

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