Genetics

An unprecedented view of gene regulation

Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from ...

Genetics

New method created for identifying genes behind brain tumors

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...

Medical research

Unexpected hope for DNA damage-related diseases

DNA damage in cells can lead to genetic diseases and a variety of cancers. To repair any damage, a process in our bodies flags repair proteins and recruits them to the damaged site. This process is called ADP-ribosylation ...

Oncology & Cancer

Mysterious gene transcripts after cancer therapy

Tumor suppressor genes protect cells from malignant transformation. If they are turned off as a result of chemical modifications in DNA, called epigenetic labels, this contributes to the development of cancer. As opposed ...

Genetics

Early lead exposure affects gene expression throughout life

A team of researchers led by North Carolina State University biologists Cathrine Hoyo and Randy Jirtle have found links between lead exposure in children and epigenetic alterations in regulatory regions of genes that are ...

page 1 from 3