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Alzheimer's disease & dementia news

Alzheimer's disease & dementia

Geneticists develop world's first bioinformatic tool to identify amyloids consisting of multiple copies of same protein

Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...

Alzheimer's disease & dementia

Obesity-induced cognitive decline: Role of brain oxidation and tocotrienols

Obesity has become a pressing worldwide health issue, with rates steadily rising over recent decades. Beyond its well-documented associations with physical health issues, such as cardiovascular disease and diabetes, obesity ...

Medications

Common HIV treatments may aid Alzheimer's disease patients

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...

Neuroscience

New mechanism uncovered in early stages of Alzheimer's disease

Alzheimer's disease (AD) remains one of the most challenging and prevalent neurodegenerative disorders, affecting millions of individuals worldwide. In a new study published in Developmental Cell, researchers from the lab ...

Alzheimer's disease & dementia

A new diagnostic model offers hope for Alzheimer's

A new mathematical model offers hope for better prediction and treatment of Alzheimer's disease. Most mathematical models of Alzheimer's are theoretical, focusing on short term molecular and cellular-level changes that cannot ...

Genetics

Newly found genetic variant defends against Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...

Alzheimer's disease & dementia

Human neuron model paves the way for new Alzheimer's therapies

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease ...