Research links age-related inflammation, microglia and Alzheimer's disease
Stanford researchers have uncovered a potential role for a protein called TREM1 in the development of age-related inflammation, cognitive decline, and Alzheimer's disease. This discovery could pave the way for new therapeutic ...
11 hours ago
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Unlocking how to use mRNA to target Alzheimer's disease
Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.
10 hours ago
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Patients with delirium more likely to develop dementia, finds study
University of Queensland researchers have found older patients who experience delirium are three times more likely to develop dementia. Professor Ruth Hubbard from UQ's Center for Health Services Research (CHSR) said the ...
11 hours ago
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Generation of tau dephosphorylation-targeting chimeras for the treatment of tauopathies
Accumulation of pathologic tau protein plays a pivotal role in the neurodegeneration of Alzheimer's disease (AD) and many other tauopathies. Thus, amelioration of pathological tau aggregates in the brain is an important direction ...
5 hours ago
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People experiencing homelessness more likely to develop dementia at younger ages, study finds
Dementia in unhoused people was 1.9 times greater than the general population, with a higher prevalence for age groups younger than 85 years, according to new research from Lawson Health Research Institute and ICES.
Mar 27, 2024
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Memory self-test via smartphone can identify early signs of Alzheimer's disease
Dedicated memory tests on smartphones enable the detection of "mild cognitive impairment," a condition that may indicate Alzheimer's disease, with high accuracy. Researchers from DZNE, the Otto-von-Guericke University Magdeburg ...
Mar 27, 2024
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Risk factors for faster aging in the brain revealed in new study
In a new study published in Nature Communications, researchers investigated the genetic and modifiable influences on fragile brain regions by looking at the brain scans of 40,000 UK Biobank participants aged over 45.
Mar 27, 2024
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Understanding the role of microglia in Alzheimer's disease
Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's. The exact mechanism behind this contribution is not ...
Mar 27, 2024
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Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham heart study
Dementia refers to a set of symptoms marked by a decline in cognitive abilities, including memory, language, reasoning and everyday tasks. It can result from various causes, such as Alzheimer's disease, vascular problems, ...
Mar 27, 2024
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From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues
A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries has published a paper in eLife. The study identifies brain energy metabolism dysfunction leading to altered pH ...
Mar 26, 2024
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Human brains are getting larger: That may be good news for dementia risk
A new study by researchers at UC Davis Health found human brains are getting larger. Study participants born in the 1970s had 6.6% larger brain volumes and almost 15% larger brain surface area than those born in the 1930s.
Mar 26, 2024
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Research team identifies new treatment target for Alzheimer's disease
Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease—PDE4B. Their work is published in Neuropsychopharmacology.
Mar 26, 2024
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Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer
Researchers at the USC Leonard Davis School of Gerontology have discovered a genetic mutation in a small mitochondrial protein that may promote longevity, preserve cognitive function, and protect against Alzheimer's disease ...
Mar 25, 2024
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How diabetes might lead to Alzheimer's: Study suggests the liver is key
New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease.
Mar 25, 2024
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We created a VR tool to test brain function. It could one day help diagnose dementia
If you or a loved one have noticed changes in your memory or thinking as you've grown older, this could reflect typical changes that occur with aging. In some cases though, it might suggest something more, such as the onset ...
Mar 25, 2024
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Tony Bennett's struggle with Alzheimer's revealed
As Tony Bennett releases what may well be his last album, his family has disclosed that the 1950s crooner who became popular with younger audiences decades later has Alzheimer's disease.
Mar 25, 2024
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New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late
Mild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the key takeaway of two recent studies from our team.
Mar 24, 2024
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Is your blood aging your brain? It might increase your dementia risk
By 2050, the global population of adults 60 and older will approximately double, leading to upward of 153 million dementia cases. That's why University College Cork neuroscience professor Yvonne Nolan and Ph.D. student Sebastian ...
Mar 24, 2024
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