Clinical trial: Some sarcoma patients improve with T cell immunotherapy
A clinical trial led by researchers at Washington University School of Medicine in St. Louis has shown that a T cell immunotherapy—in which the patients' own T cells are genetically modified to attack and kill cancer cells—is ...
22 hours ago
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Cancer-predisposition variants associated with adverse outcomes in rhabdomyosarcoma
Germline cancer-predisposition variants (CPVs) can be helpful in predicting risk in some pediatric cancers. However, CPV risk association in children with rhabdomyosarcoma has not been well studied. A new report led by researchers ...
16 hours ago
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Predicting infection risk in childhood cancer
A statistical model can accurately predict the risk of bloodstream infections in a subset of children with cancer, according to a study published in the Journal of Clinical Oncology.
20 hours ago
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AI-driven attention mechanisms aid in streamlining cancer pathology reporting
Artificial Intelligence researchers have taken a major step forward in using AI in the fight against cancer.
20 hours ago
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Improving the world's most potent cancer drug
Fourteen mice scurried around in laboratory cages, eating, sniffing, and running peacefully. You would never guess that, several weeks earlier, half of them had received five times the lethal dose of a leading chemotherapy ...
17 hours ago
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New study shows association of historical housing discrimination and shortfalls in colon cancer treatment
A nationwide study of 196 cities shows that housing discrimination from 90 years ago still casts a historical shadow of inequities in colon cancer care today, S.M. Qasim Hussaini, M.D., of the University of Alabama at Birmingham ...
17 hours ago
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Study shows improved outcomes in hospitals accredited for rectal cancer surgery
Hospitals accredited by the American College of Surgeons (ACS) National Accreditation Program for Rectal Cancer (NAPRC) demonstrate significantly better outcomes for patients undergoing rectal cancer surgery compared to non-accredited ...
17 hours ago
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Longer exclusive breastfeeding may lower risk for childhood hematologic cancers
Exclusive breastfeeding duration of at least three months may decrease the risk for childhood hematologic cancers, according to a study published online March 26 in JAMA Network Open.
20 hours ago
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Researchers discover molecule that promotes production of cancer cells in triple-negative breast cancer
A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast ...
20 hours ago
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Study flips treatment paradigm in bilateral Wilms tumor, shows resistance to chemotherapy may be good
Resistance to chemotherapy is typically associated with poor outcomes for patients with cancer. However, St. Jude Children's Research Hospital scientists demonstrated that in bilateral Wilms tumor (cancer in both kidneys) ...
19 hours ago
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Malpractice trends involving active surveillance across cancers
Active surveillance is an established practice for managing certain low-risk cancers that are unlikely to cause harm. It is an increasingly common and effective way to manage certain early-stage cancers, including those in ...
21 hours ago
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Some cancer patients can find it hard to tell family and friends
Ever since Anthony Bridges found out he had prostate cancer six years ago, he hasn't stopped talking about it. He told his Facebook friends immediately.
19 hours ago
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Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments
Neuroblastoma, one of the most common childhood cancers, is classified as a developmental cancer because it arises prenatally during the formation of organs and tissues. It originates from cancer cells that develop in neuroblasts, ...
Mar 28, 2024
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'Exhausted' immune cells in healthy women could be target for breast cancer prevention
Researchers at the University of Cambridge have created the world's largest catalogue of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene mutations.
Mar 28, 2024
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Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types
A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published in Science Advances.
Mar 27, 2024
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Researchers turn back the clock on cancer cells to offer new treatment paradigm
St. Jude Children's Research Hospital scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. ...
Mar 27, 2024
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Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies
Using novel machine learning tools developed at Stanford Medicine, researchers have mapped three distinct cellular configurations that correspond to clinical outcomes for patients with a rare, difficult-to-treat cancer called ...
Mar 27, 2024
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Investigating mechanisms of aggressive glioblastoma tumor growth
Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature ...
Mar 27, 2024
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