It's not often that two articles in the same marquee seem to have significant connections to each other. Phys Org has one article claiming video gaming can create new types of neurons and this article says that prevention of socialization can affect the nature of the brain in a host of areas.
The question can be raised does obsessive video gaming constitute a form of social isolation? Even if there are people on the screen, there isn't necessarily socialization! Consider the huge number of violent crimes, these days, many by young people with, basically, not necessarily entirely formed minds and brains. The article, for example, mentions "hyper sensitivity to threatening stimuli". The article only mentions mice staying frozen long after a threat is gone. Treated a way they don't like, young people may be temporarily frozen, but then lash out with means suggested by the video games.

How I lash out is governed by events happening to and around me as a very young child. Video games never had the emotional impact of personal violence given or received from family and neighbors.
"...does obsessive video gaming constitute a form of social isolation?" can be investigated further now with the benchmark chemical marker for isolation.
That answer could change attitudes at many levels.