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Medical research

Study reports new compound that halts replication of COVID by targeting 'Mac-1' protein in cell models

Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets "Mac-1," ...

Diseases, Conditions, Syndromes

Study confirms effectiveness of bivalent COVID-19 vaccine

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to ...

Medications

Treatment for deadly superbug C. diff may be weakening

The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston ...

Diseases, Conditions, Syndromes

Improving health communication to save lives during epidemics

During epidemics of Ebola, COVID-19, Zika and other public health emergencies, effective communication of public health messages is crucial to control the spread of disease, maintain public trust, and encourage compliance ...

Diseases, Conditions, Syndromes

New tool helps identify babies at high risk for RSV

A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under age 1 to receive a preventive medication before RSV season (October-April), ...

Diseases, Conditions, Syndromes

Bird flu in humans? Experts see little risk

The discovery of traces of the bird flu virus in pasteurized cow milk in the United States sparked questions over whether the disease could spread to humans, but experts say there is little risk from food contamination.

Diseases, Conditions, Syndromes

New algorithm could provide early warning for asthma attacks

A University of Texas at Dallas researcher and his international colleagues have developed an algorithm that might one day provide early medical alerts about the onset of asthma attacks or other respiratory problems.

Genetics

Mosaics of predisposition found to cause skin disease

Clarifying the cause of a skin disease had led to the discovery of a new disease-causing gene, a new category of diseases, and new perspectives for both counseling and therapy. The discovery is the first time that epigenetic ...

Medical research

Research analyzes government intervention and COVID-19 pandemic

While there's a strong determination worldwide to return to a new normal in a post-COVID world, the pandemic is nearly impossible to forget. A large amount of data also provides insight we may not want to move past just yet—how ...

Diseases, Conditions, Syndromes

Computer prompts could reduce empiric antibiotic use for UTI

For non-critically ill patients with urinary tract infection (UTI), computerized provider order entry (CPOE) prompts providing patient- and pathogen-specific multidrug-resistant organism (MDRO) risk estimates can reduce empiric ...

Genetics

New strategy for assessing natural history of leukodystrophies

Natural history studies serve as an important standard in medical research because they analyze demographic, genetic, environmental and other variables to better understand how a disease develops and its clinical outcomes.

Diseases, Conditions, Syndromes

DNA vaccine against Zika performs well in tests on mice

In Brazil, researchers at the University of São Paulo (USP) and the Pernambuco division of Oswaldo Cruz Foundation (FIOCRUZ) are developing a Zika vaccine. The formulation was tested on mice and found to be efficacious, ...

Diseases, Conditions, Syndromes

Human cases of bird flu 'an enormous concern': WHO

The World Health Organization voiced alarm Thursday at the growing spread of H5N1 bird flu to new species, including humans, who face an "extraordinarily high" mortality rate.