The science of replacing mitochondrial DNA and what remains unknown
1 hour ago
Mitochondrial replacement therapy (MRT) has now been used in humans to conceive a "three-parent baby" to prevent inherited mitochondrial disorders, but there remain questions about the effectiveness of the process.
Epigenetic factors linked to obesity-related disease
17 hours ago
Obesity has been linked to "letter" changes at many different sites in the genome, yet these differences do not fully explain the variation in people's body mass index (BMI) or why some overweight people develop health complications ...
Are you ready to explore baby's genome?
19 hours ago
When you have a baby, a nurse or a phlebotomist performs a heel stick to take a few drops of blood from your infant and sends it off to a state lab for a battery of tests. Most of the time, you never hear about the results ...
Study applies game theory to genomic privacy
22 hours ago
It comes down to privacy—biomedical research can't proceed without human genomic data sharing, and genomic data sharing can't proceed without some reasonable level of assurance that de-identified data from patients and ...
Improving the view on the genetic causes of retinitis pigmentosa
23 hours ago
Progressive development of night blindness and tunnel vision, sometimes from the early age of 2, are trademarks of retinitis pigmentosa. Being the most common inherited disorder of the retina, retinitis pigmentosa affects ...
Study shows that genetics play an important role in the attainment of education and number of offspring
Jan 17, 2017 report
(Medical Xpress)—A team of researchers with members from Iceland, the U.K. and the Netherlands has found a genetic factor that plays a role in how much education a person might attain over their lifetime and that the factor ...
Best treatment option written in cancer's genetic script: AML study finds personalised therapy is possible
Jan 16, 2017
An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer. Details of ...
Potentially reversible changes in gene control 'prime' pancreatic cancer cells to spread
Jan 16, 2017
A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence ...
Mutations responsible for cleft palate and related birth defects identified
Jan 12, 2017
Researchers located a novel gene mutation causing cleft lip and cleft palate defects, which slows the turnover of hyaluronan, an important component of the hard palate. Martina Muggenthaler working with Prof Andrew Crosby, ...
'Mysterious' non-protein-coding RNAs play important roles in gene expression
Jan 12, 2017
In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from the protein-coding regions ...