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HIV & AIDS news
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Study confirms how RNA chemical modifications benefit HIV-1
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.
Apr 11, 2024
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Scientists identify pro-aging 'sugar signature' in the blood of people living with HIV
The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living ...
Apr 10, 2024
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Small protein plays big role in chronic HIV infection
NeuroHIV refers to the effects of HIV infection on the brain or central nervous system, and to some extent, the spinal cord and peripheral nervous system. A collection of diseases, including neuropathy and dementia, neuroHIV ...
Apr 4, 2024
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Early coronary disease, impaired heart function found in asymptomatic people with HIV
A new study has found that increased coronary vessel wall thickness is significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV. The study is published in Radiology: ...
Apr 4, 2024
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'It's the greatest living experiment': Pitt Men's Study marks 40 years of AIDS research
In a Pittsburgh hospital in the early 1980s, Charles Rinaldo saw a young, previously healthy gay man critically ill with a virus usually only seen in weakened immune systems.
Apr 1, 2024
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The pioneer of America's embattled global HIV program recalls the hope after years of despair
Through his office window at what was then one of Africa's few modern clinics dealing with HIV and AIDS, the man who now oversees the United States' threatened global AIDS effort used to hear the sound of taxis pulling up ...
Apr 1, 2024
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Exploring the relationship between HIV pre-exposure prophylaxis and the incidence of chlamydia, gonorrhea and syphilis
In their research article published in Eurosurveillance, von Schreeb et al. challenge existing assumptions regarding the relationship between the use of HIV pre-exposure prophylaxis (PrEP) and the incidence of bacterial sexually ...
Mar 28, 2024
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Half of those with HIV in developed countries are at least age 50, at higher risk of frailty and multiple comorbidities
A new research review to be presented at a pre-congress day for this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2024) will focus on the growing prevalence of HIV in older adults, with—using ...
Mar 27, 2024
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Implantable device delivers HIV antiviral with more potency than oral drugs
A team from Houston Methodist Research Institute recently showed that a nanofluidic implant delivered an HIV drug that achieved more potency than other forms of drug administration (oral) and other HIV drugs.
Mar 26, 2024
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New study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir
By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic. An international team of researchers led by Eric Arts, professor at the ...
Mar 26, 2024
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Abuse found to increase risk for cardiovascular disease among women with HIV
A study by Allison Appleton, Mark Kuniholm and Elizabeth Vásquez in the School of Public Health's Department of Epidemiology and Biostatistics is the first to establish a connection between physical and sexual abuse and ...
Mar 21, 2024
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Drug candidate may 'unmask' latent HIV-infected cells, mark them for destruction
University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
Mar 19, 2024
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HIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology, increasing hopes of cure
New research presented early ahead of this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) from a team of researchers in the Netherlands shows how the latest ...
Mar 19, 2024
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Long-acting injectable ART superior to standard care for poorly adherent people with HIV
For people with HIV (PWH) and a history of suboptimal adherence to antiretroviral therapy, long-acting injectable treatment with cabotegravir and rilpivirine (LAI) is superior to oral standard of care (SOC), according to ...
Mar 13, 2024
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Improving care of hospitalized patients with HIV in Tanzania
Researchers at Weill Cornell Medicine have shown that three months of social worker follow-up support to people hospitalized with HIV in Tanzania had health benefits at low cost. The protocol shortened the time it took participants ...
Mar 11, 2024
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Nurse-led strategy found to reduce cardiovascular risk factors for people with HIV
Nurse-led management can lower cardiovascular risk factors among individuals with HIV receiving antiretroviral therapy, according to a study published online March 5 in JAMA Network Open.
Mar 11, 2024
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
Mar 8, 2024
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Release of inhibitory pathways may promote immune response to HIV
Recent work from the laboratory of Elena Martinelli, Ph.D., MPH, professor of Medicine in the Division of Infectious Diseases and of Microbiology–Immunology, has discovered how inhibiting an immune cell singling pathway ...
Mar 7, 2024
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Children surpass a year of HIV remission after treatment pause
Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to a presentation today at the 2024 Conference ...
Mar 6, 2024
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