Team reports progress in developing specific immunotherapies for type 1 diabetes
Researchers from Germans Trias i Pujol Research Institute (IGTP) and Ahead Therapeutics SL have been exploring a treatment based on liposome-type nanoparticles to address the autoimmunity of type 1 diabetes for years. A study ...
15 hours ago
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Mutations do not predict the severity of current variants of SARS-CoV-2, finds study
New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two most prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants ...
19 hours ago
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Gut microbiome: Meet Roseburia intestinalis—the energy-producing bacterium that helps us fight against disease
The hundreds of species of microorganisms that comprise the microbiome all have different, unique roles.
18 hours ago
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Researchers discover a signaling molecule in neuroblastoma immunosuppression and aggressiveness
The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma ...
Mar 15, 2024
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Researchers discover key metabolic process responsible for rapid immune responses
Researchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, ...
Mar 15, 2024
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Researchers gain insight into why T cells lose energy in solid tumors
T cells are often called "assassins" or "killers" because they can orchestrate and carry out missions to hunt down bacteria, viruses, and cancer cells throughout the body. Mighty as they may be, recent research has shown ...
Mar 15, 2024
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Machine learning classifier accelerates the development of cellular immunotherapies
Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious ...
Mar 15, 2024
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New technique opens up study of immune response to cancer based on DNA locked in old archive cancer samples
Scientists have developed an improved technique for reading the genetic material associated with the body's immune response to cancer, making it possible to study tissue samples that have been stored in archives for decades.
Mar 15, 2024
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Exploring why some newborns develop severe infections
Compared to adults, newborns are highly susceptible to infections and these infections can cause serious health complications and even death.
Mar 15, 2024
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Simple blood test could predict risk of long-term COVID-19 lung problems
UVA Health researchers have discovered a potential way to predict which patients with severe COVID-19 are likely to recover well and which are likely to suffer "long-haul" lung problems. That finding could help doctors better ...
Mar 15, 2024
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Study uncovers novel mechanisms behind food allergies
A recent Northwestern Medicine study has shed light on the mechanisms of a specific protein that is necessary for the production of IgA antibodies in the gut in response to food allergens, according to findings published ...
Mar 15, 2024
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Scientists compete to make best predictions about pertussis vaccine
Scientists love a challenge. Or a friendly competition. Now, scientists at La Jolla Institute for Immunology (LJI) have recently published the results of a competition that put researchers to the test. For the competition, ...
Mar 14, 2024
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Researchers may have found key to deprogram cells that lead to transplant rejection
Houston Methodist researchers identified a troublesome subset of T-cells in transplant recipients that may be a more effective therapeutic target for preventing transplant rejection in patients.
Mar 14, 2024
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Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds
A new study from the Perelman School of Medicine at the University of Pennsylvania shows that antibody responses to new SARS-CoV-2 variant infections and vaccinations are powerfully shaped by prior exposures to earlier SARS-CoV-2 ...
Mar 14, 2024
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Q&A: The rising rates of immunosuppression among US adults
Early in the COVID-19 pandemic, as it became clear that people with suppressed immune systems were particularly vulnerable to the worst of the virus, public health officials prioritized their protection. Leaders presented ...
Mar 14, 2024
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A new strategy to attack aggressive brain cancer shrank tumors in two early tests
A new strategy to fight an extremely aggressive type of brain tumor showed promise in a pair of experiments with a handful of patients.
Mar 14, 2024
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Studying use of patients' own reprogrammed cells to attack cancer as alternative to more chemo
A process of taking patients' own cells and reprogramming them to fight cancer has been a last-ditch option for blood cancer patients when nothing else worked, but a new study underway in Aurora is trying to determine whether ...
Mar 14, 2024
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Early clinical trial results show 'dramatic and rapid' regression of glioblastoma after next generation CAR-T therapy
A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment. In a paper published in the New ...
Mar 13, 2024
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