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Immunology news
Immunology
Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses
The COVID-19 pandemic is over, but the virus that caused it is still here, sending thousands of people to the hospital each week and spinning off new variants with depressing regularity. The virus's exceptional ability to ...
May 18, 2024
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Immunology
Unlocking the body's defenses: Understanding immunotherapy
In the battle against diseases, the human body boasts an intricate defense network capable of identifying and neutralizing threats—the immune system. It serves as a guardian, constantly patrolling the body to keep it safe ...
May 18, 2024
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Gut bacteria enhance cancer immunotherapy in mouse study
Roughly one in five cancer patients benefit from immunotherapy—a treatment that harnesses the immune system to fight cancer. Such an approach to beating cancer has seen significant success in lung cancer and melanoma, among ...
May 17, 2024
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Researchers make strides in microbiome-based cancer therapies via iron deprivation in the tumor microenvironment
A team from POSTECH and ImmunoBiome has made a potential breakthrough in the fight against cancer. Their research, published in the May issue of Nature Immunology, explores a dietary-derived bacterial strain, IMB001. This ...
May 17, 2024
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Research finds the protein VISTA directly blocks T cells from functioning in immunotherapy
A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.
May 17, 2024
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Cell types and molecules usually associated with autoimmune diseases found to be normal components of gut immunity
Researchers in the Peter Gorer Department of Immunobiology have identified that features of the immune system that were previously considered to be characteristics of autoimmune diseases are normal components of the immune ...
May 17, 2024
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Scaffolding sensors detect early evidence of organ transplant rejections in mice
A new microporous scaffold functions as a minimally-invasive surveillance method to identify rejection prior to graft injury in a mouse model, according to a study published in Science Advances.
May 17, 2024
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Study finds antioxidant dietary supplement may help counter systemic sclerosis
Autoimmune diseases occur when the body's immune system attacks healthy cells instead of protecting them. Systemic sclerosis (SSc) is one such autoimmune condition characterized by faulty circulatory and immune systems, leading ...
May 17, 2024
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FDA approves new drug for deadly lung cancer
The U.S. Food and Drug Administration on Thursday approved a new drug to treat patients with an advanced form of deadly lung cancer.
May 17, 2024
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Researchers identify immunosuppressive pathway that helps newborn hearts regenerate in mouse models
When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
May 16, 2024
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The importance of the rhythmicity of the immune system for tumor growth
By examining the immune modulations of tumors during the day, scientists from the University of Geneva and the LMU Munich are demonstrating their impact on the diagnosis and management of patients.
May 16, 2024
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Biomarker could improve prediction of response to immunotherapy in melanoma
If melanoma spreads, there are various therapies that can be used. However, there is still insufficient research into who responds to which therapy and whether resistance may develop over time.
May 16, 2024
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Review explores cell-based immunotherapies for sepsis
Imagine the human body mounting an excessively heightened reaction to an infection, causing multiple organ failures and posing a risk of death. This condition, recognized as sepsis, affects approximately 49 million individuals ...
May 16, 2024
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Study reveals immunotherapy's potential in boosting immune systems of older individuals
Published in Nature Aging, University of Minnesota Medical School researchers have provided new insight into enhancing immune responses in older individuals and the potential for using immunotherapy to make older adults less ...
May 15, 2024
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Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer, Phase III study finds
Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy—given before and after surgery—significantly improved event-free survival (EFS) in patients with resectable early-stage non-small ...
May 15, 2024
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This time, it's personal: Enhancing patient response to cancer immunotherapy
Immunotherapy has revolutionized the way we treat cancer in recent years. Instead of targeting the tumor itself, immunotherapies work by directing patients' immune systems to attack their tumors more effectively. This has ...
May 15, 2024
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New study identifies mechanism of immune evasion of SARS-CoV-2 and variants
A new study has revealed important insights into how SARS-CoV-2 and its variants escape the immune system. The findings pave the way for new therapeutic approaches against COVID-19.
May 15, 2024
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Breaking bad blood: How rogue neutrophils help lung cancer spread
Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide. Central to its development is the tumor microenvironment, which involves a complex interplay with ...
May 15, 2024
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Researchers explore the role of of transposable elements in myocarditis
Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation.
May 15, 2024
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Iron fuels immune cells—and it could make asthma worse
You've likely heard that you can get iron from eating spinach and steak. You might also know that it's an essential trace element that is a major component of hemoglobin, a protein in red blood cells that carries oxygen from ...
May 15, 2024
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