Researchers provide evidence linking 'leaky gut' to chronic inflammation
Apr 20, 2017
With the help of genetically engineered mice, scientists at the Massachusetts General Hospital (MGH) are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays ...
Experimental drug targets nucleus of allergen-sensitized cells
Apr 18, 2017
Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...
Gut microbes contribute to age-associated inflammation, mouse study finds
Apr 12, 2017
Inflammation increases with age and is a strong risk factor for death in the elderly, but the underlying cause has not been clear. A study published April 12 in Cell Host & Microbe reveals that gut microbes are one of the ...
Tailored intervention in acute and chronic inflammation
Apr 06, 2017
Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage. A systematic analysis of their interactions by researchers from Ludwig-Maximilians-Universitaet (LMU) ...
Asthmatic schoolchildren are 'uncomfortable' using their inhalers
Mar 29, 2017
Poor asthma control and knowledge are common in children with doctor-diagnosed asthma, according to research by Queen Mary University of London (QMUL).
Cholesterol drug shown to reduce inflammation, other factors in patients
Mar 24, 2017
Statin drugs are widely used to manage high cholesterol and reduce the risk of cardiovascular disease. But in a new review of more than 50 studies, researchers cite reductions in liver inflammation and improvements in other ...
Possible new target for treatment of multiple sclerosis found
Mar 23, 2017
In the relentless battle against multiple sclerosis (MS), U of A researchers recently discovered an entirely new cellular mechanism—an underlying defect in brain cells—that may to be blame for the disease, and a potential ...
Study brings hope of a new treatment for asthma sufferers
Mar 01, 2017
Improved treatments for people with severe asthma are a 'step closer' after a research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing.
Could a ketogenic diet alleviate gout?
Feb 28, 2017
More than 8 million individuals in the United States have gout, a disease that can cause intense recurrent episodes of debilitating pain, inflammation, and fever. The cause of gout is the accumulation of urate crystals in ...
Biologists control gut inflammation by altering the abundance of resident bacteria
Feb 16, 2017
Numerous human diseases, including inflammatory bowel disease, diabetes and autism spectrum disorders have been linked to abnormal gut microbial communities, or microbiomes, but an open question is whether these altered microbiomes ...