Nucleic Acids Research is a peer-reviewed scientific journal published by Oxford University Press. It covers research on nucleic acids, such as DNA and RNA, and related work. Some of its content is available under an open access license. According to the Journal Citation Reports, the journal s 2010 impact factor is 7.836. The journal publishes two yearly special issues, one dedicated to biological databases, published in January since 1993 and the other on biological web servers, published in July since 2003.
Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes. In people with cancer, ASOs have the potential to block messages that encourage ...
Apr 16, 2024
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Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages. Some of these changes, particularly when they occur in genes, can be instrumental during the development ...
Apr 10, 2024
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Recent research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by ...
Apr 10, 2024
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Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic ...
Jan 5, 2024
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University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhancer reprogramming, occurs ...
Sep 29, 2023
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Each cell in the body stores its genetic information in DNA in a stable and protected form that is readily accessible for the cell to carry on its activities. Nevertheless, mutations—changes in genetic information—occur ...
Aug 3, 2023
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Precision medicine seeks to adapt treatments to the characteristics of each patient. Genome studies are providing more and more data to achieve this, but this very abundance of information is hampering the task: Doctors must ...
Jun 20, 2023
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A new study brings precision to the understanding of which antibiotics work best for acne treatment and why. This is important for two key reasons. Acne affects nearly everyone at some point in life—it is, in fact, the ...
Mar 8, 2023
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Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.
Feb 21, 2023
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Researchers from the Epigenetics and Immune Disease Lab at the Josep Carreras Leukaemia Research Institute have recently shown that vitamin C improves the immunogenic properties of dendritic cells in vitro.
Nov 2, 2022
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