Potential brain-machine interface for hand paralysis

January 15, 2018 , Society for Neuroscience
The combined approach of a Brain-Machine Interface (BMI) and transcranial magnetic stimulation used in this study, showing a different, more advanced robot device. Delivering brain stimulation and robotic motor feedback simultaneously during rehabilitation may be beneficial for patients who have lost voluntary muscle control. Credit: Gharabaghi lab, University of Tuebingen, Germany

A brain-machine interface that combines brain stimulation with a robotic device controlling hand movement increases the output of pathways connecting the brain and spinal cord, according to a study of healthy adults published in the Journal of Neuroscience. This work could have implications for restoring function in stroke patients with hand paralysis.

Alireza Gharabaghi and colleagues asked participants to imagine opening their hand without actually making any movement while their hand was placed in a device that passively opened and closed their fingers as it received the necessary input from their brain activity. The researchers demonstrate that stimulating the hand area of the motor cortex at the same time, but not after, the initiated increased the strength of the neural signal, most likely by harnessing the processing power of additional neurons in the corticospinal tract.

However, the signal decreased when participants were not required to imagine moving their hand. Delivering and robotic motor feedback simultaneously during rehabilitation may therefore be beneficial for patients who have lost voluntary muscle control.

The Brain-Machine Interface (BMI) setup applied in this study. Participants imagine opening their hand without actually making any movement while their hand is placed in a device that passively opens and closes their fingers as it receives the necessary input from their brain activity. Credit: Gharabaghi lab, University of Tuebingen, Germany

More information: Recruitment of additional corticospinal pathways in the human brain with state-dependent paired associative stimulation, Journal of Neuroscience (2018). DOI: 10.1523/JNEUROSCI.2893-17.2017

Journal information: Journal of Neuroscience

Provided by Society for Neuroscience