New study reveals potential therapeutic approach to enhance keratinocyte migration in cutaneous wound healing

New study reveals potential therapeutic approach to enhance keratinocyte migration in cutaneous wound healing
Journal of Medicinal Food

Researchers have identified a new mechanism involving ginsenoside Rb1, which has the ability to stimulate keratinocyte migration and promote cutaneous wound healing. They report the results of a study showing that Rb1 enhances keratinocyte migration in an article published in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The researchers demonstrated that Rb1 significantly increases the production of sphingosine-1-phosphate (S1P), which is a signaling factor in keratinocytes known to stimulate wound repair through greater keratinocyte migration.

More information: Kyong-Oh Shin et al. Ginsenoside Rb1 Enhances Keratinocyte Migration by a Sphingosine-1-Phosphate-Dependent Mechanism, Journal of Medicinal Food (2018). DOI: 10.1089/jmf.2018.4246

Provided by Mary Ann Liebert, Inc., Publishers
Citation: New study reveals potential therapeutic approach to enhance keratinocyte migration in cutaneous wound healing (2018, September 26) retrieved 19 April 2024 from https://medicalxpress.com/news/2018-09-reveals-potential-therapeutic-approach-keratinocyte.html
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