The Institute for Research in Biomedicine (IRB Barcelona) is an institution engaged in basic and applied research at the interface between molecular and cell biology, computational and structural biology and chemistry, with experts in proteomics, genomics, biostatistics and advanced digital microscopy. The institute was created by the Government of Catalonia in October 2005 and is located at the Barcelona Science Park (Parc Científic de Barcelona - PCB). The director of the Institute is Prof. Joan J. Guinovart i Cirera and the adjunct director is Prof. Joan Massagué Solé. IRB Barcelona was recently named a "Severo Ochoa Centre of Excellence" by the Spanish Ministry of Science and Innovation (2011), current Ministry of Economy and Competitiveness.
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Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages. Some of these changes, particularly when they occur in genes, can be instrumental during the development ...
Apr 10, 2024
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Pediatric cancer, also known as developmental cancer, is rare. Around 400,000 new cases are diagnosed worldwide each year. The likelihood of a child developing two independent cancers during childhood is extremely low. However, ...
Mar 19, 2024
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Cancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells (also called "zombie cells"). While senescent cells do not reproduce, ...
Jan 24, 2024
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Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, aging, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA replication ...
Jan 10, 2024
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Fibrosis is associated with various chronic and life-threatening conditions, including pulmonary fibrosis, liver cirrhosis, kidney disease, and cardiovascular diseases, among others. These conditions collectively contribute ...
Dec 14, 2023
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Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and control the rate at which ...
Dec 4, 2023
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Vitamin B12 is a well-known micronutrient that has long been acknowledged for its essential role in maintaining nerve function, supporting red blood cell production, and facilitating DNA synthesis, all vital processes for ...
Nov 16, 2023
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Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumor remains localized in the breast, survival rates are remarkably high, at around ...
Nov 9, 2023
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A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d'Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) ...
Aug 10, 2023
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A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging. ...
Jun 8, 2023
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