Salk Institute

Immunology

Reducing stress on T cells makes them better cancer fighters

Even for killer T cells—specialized immune cells—seeking and destroying cancer cells around the clock can be exhausting. If scientists can understand why killer T cells become exhausted, then they can create more resilient ...

Oncology & Cancer

'Super-enhancer' molecules super-charge pancreatic tumor growth

Pancreatic cancers are among the most aggressive, deadly tumor types, and for years, researchers have struggled to develop effective drugs against the tumors. Now, Salk Institute researchers have identified a new set of molecules ...

Immunology

Investigating why we lose fat and muscle during infection

Although infections can present with many different symptoms, one common symptom is the loss of fat and muscle, a process called wasting. Salk scientists wanted to know whether wasting was beneficial in fighting infections.

Diseases, Conditions, Syndromes

All the immunity, none of the symptoms, through dietary intervention

Worldwide, more than a million deaths occur each year due to diarrheal diseases that lead to dehydration and malnutrition. Yet, no vaccine exists to fight or prevent these diseases, which are caused by bacteria like certain ...

Immunology

Mapping the development of infection-fighting immune cells

The immune system protects the body from invaders, such as bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs. Specialized immune cells, called cytotoxic T cells, can develop into short-lived ...

Neuroscience

New way to model human brain immune cells

Situated at the intersection of the human immune system and the brain are microglia, specialized brain immune cells that play a crucial role in development and disease. Although the importance of microglia is undisputed, ...

Neuroscience

How aggression-promoting brain peptide works in fruit flies

In addition to communicating with neurotransmitters, the brain also uses small proteins called neuropeptides. Neuropeptides send signals between neurons, working similarly to neurotransmitters but with key differences like ...

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