University of Geneva

Neuroscience

How to generate new neurons in the brain

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...

Alzheimer's disease & dementia

An action plan to prevent Alzheimer's disease

Memory loss, behavioral changes, cognitive deficits: Alzheimer's disease leads to a dramatic loss of autonomy for those affected and has a heavy impact on health costs. Its prevention has become a real social challenge. An ...

Neuroscience

Managing emotions better could prevent pathological aging

Negative emotions, anxiety and depression are thought to promote the onset of neurodegenerative diseases and dementia. But what is their impact on the brain and can their deleterious effects be limited?

Oncology & Cancer

Fighting cancer is more efficient at dawn, study finds

The ability of tumors to take hold and grow depends, among other things, on the effectiveness of the immune system in fighting them. Cancer cells, like pathogens, can be identified and targeted by a specific immune response. ...

Oncology & Cancer

Localizing BRCA gene mutations to better treat ovarian cancer

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

Medical research

Overcoming resistance to colon cancer treatment

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs. ...

Psychology & Psychiatry

Too much motivation affects our decision-making

In a good or a bad mood, focused or distracted, our internal states directly influence our perceptions and decision-making. While the role of motivation on the performance of behavioral tasks has been known for more than ...

Genetics

Zinc could treat a rare genetic disorder

Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene. In order to understand the ...

Medical research

Awakening dormant cells to fight cancer

The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...

Diabetes

Diabetes: When circadian lipid rhythms go wrong

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of ...

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