Neuroscience
Lactate triggers genes that modify brain activity
A genome-wide study led by Dean Pierre Magistretti sheds light on the mechanisms through which lactate regulates long-term memory formation and neuroprotection.
Feb 12, 2019
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Page 3 - News tagged with adenine
Medical research
Researchers develop new method to diagnose, monitor chronic wounds
Researchers at the University of Arkansas have developed a new approach to diagnosing and monitoring chronic skin wounds, such as diabetic foot ulcers and pressure wounds.
Nov 20, 2018
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Medical research
NAD can restore mitochondrial function and energy production in MTDPS liver-like cells
Mitochondria are responsible for supplying the cell with energy in the form of ATP through oxidative phosphorylation. There is a group of rare, autosomal recessive disorders, known as Mitochondrial DNA Depletion Syndromes ...
Nov 6, 2018
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Medical research
Could vitamin B3 treat acute kidney injury?
Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries. The condition causes a build-up ...
Aug 20, 2018
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Medical research
Researchers find glycolysis links to gene transcription via NAD+
A team of researchers at the University of Texas has found NAD+ synthesis and consumption integrate glucose metabolism and adipogenic transcription during adipocyte differentiation. In their paper published in the journal ...
Immunology
Study explores emerging role of NAD+ in innate and adaptive immune responses
Researchers at Brigham and Women's Hospital (BWH) have discovered a new cellular and molecular pathway that regulates CD4+ T cell response—a finding that may lead to new ways to treat diseases that result from alterations ...
Feb 23, 2018
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Alzheimer's disease & dementia
Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer's disease
The supplement nicotinamide riboside (NR) – a form of vitamin B3 – prevented neurological damage and improved cognitive and physical function in a new mouse model of Alzheimer's disease. The results of the study, conducted ...
Feb 7, 2018
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Genetics
Disruption of NAD synthesis tied to congenital malformations
(HealthDay)—For humans and mice, disruption of nicotinamide adenine dinucleotide (NAD) synthesis causes deficiency of NAD, resulting in congenital mutations, according to a study published in the Aug. 10 issue of the New ...
Aug 10, 2017
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Neuroscience
Potential target identified for preventing long-term effects of traumatic brain injury
More than 200,000 U.S. soldiers serving in the Middle East have experienced a blast-related traumatic brain injury, making it a common health problem and concern for that population.
Oct 31, 2016
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Medical research
Researchers link specific enzyme to process of metabolic dysfunction in aging
Researchers at Mayo Clinic have identified the enzyme, called CD38, that is responsible for the decrease in nicotinamide adenine dinucleotide (NAD) during aging, a process that is associated with age-related metabolic decline. ...
Jun 14, 2016
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