There was no weight gain, despite a higher energy intake, and insulin sensitivity was increased. These are the results from experiments on mice that had elevated levels of the protein BMP4 following gene therapy in a study ...
Aug 24, 2017
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Northwestern Medicine scientists have identified a novel molecular mechanism that regulates scar formation in the heart, a common manifestation of aging and nearly every form of heart disease. The discovery was published ...
Jul 13, 2017
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Bone morphogenetic proteins, commonly used off-label to enhance pediatric spinal fusion (spinal arthrodesis), did not improve revision rates for pediatric spinal fusion, according to a study presented on March 14 at the American ...
Mar 14, 2017
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Researchers have designed a 3D-printed porous scaffold for use in reconstructing ruptured anterior cruciate ligaments (ACL) in the knee and engineered it to deliver a human bone-promoting protein over an extended period of ...
Feb 27, 2017
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Doctors have found a way to manipulate wounds to heal as regenerated skin rather than scar tissue. The method involves transforming the most common type of cells found in wounds into fat cells - something that was previously ...
Jan 5, 2017
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(Medical Xpress)—A team of researchers with the Rockefeller University has identified the signals and timing that are involved during embryonic development controlling whether skin cells grow to be sweaty or hairy. In their ...
A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, has created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. The combination ...
Dec 5, 2016
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The part of the jawbone containing the tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. While dentures can be used as a tooth replacement, the ...
Aug 24, 2016
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Researchers use induced pluripotent stem cells in a mouse model to show that diseased bone growth may be stimulated by a key molecule for inflammation. Inhibition of activin-A was found to repress the bone overgrowth typically ...
Nov 30, 2015
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A new study may alleviate concerns regarding increased cancer risk for patients undergoing spinal fusion surgery with recombinant human bone morphogenetic protein (rhBMP). The study appears in November 15 issue of Spine.
Nov 12, 2015
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