Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
Mar 19, 2024
0
47
The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
Mar 18, 2024
0
20
In ovarian cancer, the abnormal expression of various metabolic enzymes in the metabolism of polyunsaturated fatty acids (PUFA) is involved in the development of tumors and immune regulation. Most ovarian cancer patients ...
Mar 14, 2024
0
0
Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
0
90
UC San Francisco researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.
Mar 5, 2024
0
38
The tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of non-tumoral cells and molecules they produce and release. The interplay between tumor cells and the TME significantly impacts ...
Mar 4, 2024
0
0
Oral cancers and precancerous mouth lesions are considered especially difficult to diagnose early and accurately.
Mar 4, 2024
0
0
Scientists have discovered a way to stop active cancer cells in their tracks—meaning they can then be eliminated by new drug treatments.
Feb 28, 2024
0
3
A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...
Feb 27, 2024
0
42
In a new editorial paper published in Oncoscience titled, "A very long and winding road: developing novel therapeutics for metastatic tumors," researcher Paul Dent from the Department of Biochemistry and Molecular Biology ...
Feb 26, 2024
0
0
