Oncology & Cancer

Scientists crack structure of enzyme complex linked to cancer

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA ...

Diseases, Conditions, Syndromes

Possible path toward first anti-MERS drugs

If you haven't heard of Middle East Respiratory Syndrome, thank geography, NGOs, and government agencies like the Centers for Disease Control and Prevention and the World Health Organization (WHO) for keeping the new disease ...

HIV & AIDS

HIV/AIDS vaccines: Defining what works

Designing an effective HIV/AIDS vaccine is something of a paradox: a good vaccine would be safe and look enough like HIV to kick-start the immune system into neutralizing the virus – but the problem is that this is exactly ...

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Oncology & Cancer

Awakening to new drugs against sleeping sickness

Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this illness (human ...

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