Published in Nature Microbiology, a study in mice finds that the microbial basis for urinary tract infections can include localized epigenetic alterations that make additional infections more likely.
Twenty years ago, after the human genome was first sequenced, geneticists began conducting large genome-wide association studies to identify genomic regions linked to human disease. In addition to DNA sequence, another stable ...
Jan 12, 2023
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In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...
Dec 22, 2022
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An epigenetic inhibitor can boost immune system activity in patients with ovarian cancer, making them more suitable for treatment with immunotherapy, according to a Northwestern Medicine study published in the Journal of ...
Jul 26, 2022
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One of the more promising biomarkers to measure biological aging is DNA methylation, an epigenetic modification that alters a specific sequence of DNA nucleotides known as CpG sites. Researchers have traditionally used epigenetic ...
Jan 10, 2022
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Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...
Aug 4, 2021
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By sequencing entire genomes for DNA modifications, and analyzing both cancer tissues and healthy ones, Hackensack Meridian Health researchers and doctors have found what could be a key to risks for cancer and other diseases: ...
Jun 29, 2020
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What is happening with Alzheimer's disease research and treatment? We heard from Maria Carrillo, chief science officer of the nationwide Alzheimer's Association, during a recent visit to San Diego. Here are some questions ...
Sep 4, 2019
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A child's risk of obesity as they grow up can be influenced by modifications to their DNA prior to birth, a new University of Southampton study has shown.
Feb 20, 2019
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QBI researchers have discovered a DNA modification that enhances our ability to extinguish fear.
Feb 19, 2019
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