In the current issue of Proceedings of the National Academy of Sciences, researchers from Nationwide Children's Hospital describe a new paradigm for treating transcription factor-driven cancers. The study focuses on Ewing ...
Sep 18, 2017
0
87
A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma. The technique, based on CRISPR and described in the pages of Stem Cell Reports, ...
May 11, 2017
0
18
Tumors of the elderly, such as breast cancer and colon cancer, accumulate thousands of DNA mutations. These genetic defects contribute to cancer-specific properties including uncontrolled growth, invasion in neighboring tissues, ...
Jan 30, 2017
0
0
The stretches of DNA between genes, littered with repeating sequences, were once considered the "junk of the genome," but scientists are learning that some of this junk is far from harmless clutter.
Nov 1, 2016
0
86
Tumours are an accumulation of cells that divide without control, accumulating hundreds of chromosomal alterations and mutations in their DNA. These alterations are triggered in part by a type of damage to the DNA known as ...
Sep 13, 2016
0
1
Researchers at the Children's Cancer Institute (Instituto do Câncer Infantil, ICI), the Federal University of Rio Grande do Sul (UFRGS), the Cancer and Neurobiology Laboratory, and the Pediatric Oncology Service at the university ...
May 19, 2016
0
32
Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.
Mar 30, 2016
0
43
A compound discovered and developed by a team of Georgetown Lombardi Comprehensive Cancer Center researchers that halts cancer in animals with Ewing sarcoma and prostate cancer appears to work against some forms of leukemia, ...
Oct 9, 2015
0
13
A University of Colorado Cancer Center study published in the journal PLoS One finds alterations in expression of genes PIK3R3 and PTEN, more commonly observed in adult tumors, in the rare, young-adult bone cancer Ewing Sarcoma, ...
Feb 3, 2015
0
15
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 (SIRT1) protein as a future treatment option ...
Jan 29, 2015
0
9
