A new study published in Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein that is overexpressed in several cancer types and promotes tumor progression.
Jan 19, 2024
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"Precision medicine," an emerging approach to health care in which a patient's genetics, diseased tissue and other factors guide clinicians to personalize treatment strategies, can dramatically improve health outcomes for ...
Jan 17, 2024
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The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes. However, HOXA9 is a difficult protein to target therapeutically, so researchers at St. Jude Children's ...
Jan 12, 2024
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A recent study used a big data multi-omics analysis to examine changes in gene expression as cells from human fallopian tubes become cancerous.
Jan 12, 2024
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Particulate matter causes health problems for those who inhale the fine droplets and particles, but the chemical composition of the mixture matters—and can vary widely across space and time.
Dec 29, 2023
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Only recently was it discovered that amino acids, the building blocks of proteins, exist in two different forms: L- and D-forms. While all natural proteins consist exclusively of L-amino acids, the function of D-amino acids ...
Dec 21, 2023
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Biliary tract cancers (BTCs) including cholangiocarcinoma (CCA) and gallbladder cancer (GBC) are becoming more prevalent globally. An effective chemotherapeutic agent for the treatment of BTCs is gemcitabine. Other novel ...
Nov 30, 2023
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Researchers from the Max Planck Institute of Psychiatry asked themselves which genetic variants might be involved in the response to stress. Using a new methodology, they were able to test more than 3,600 specific variants ...
Nov 28, 2023
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Weight gain and weight loss are not as simple as "calories in, calories out," given that countless factors affect body weight. Now, researchers from Japan have identified a gene that may serve as a master regulator of fat ...
Nov 27, 2023
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Researchers led by the University of Tsukuba conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Their results are published in the journal Diabetes.
Nov 21, 2023
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