Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria.
Feb 20, 2024
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Gene therapy adeno-associated viruses (AAVs)—viruses that can be engineered to deliver DNA to target cells—are unlikely to cause cancer-triggering insertions in humans or monkeys and may contribute to long-term efficacy, ...
Nov 6, 2023
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Severe combined immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer ...
Oct 27, 2023
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Scientists have relied on animal models as an alternative to testing on human tissues and cells for decades. But not just any organism can adequately model how human cells behave. Researchers take into account how quickly ...
Aug 8, 2023
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Bats are asymptomatic carriers of a multitude of viruses that are pathogenic to most other mammals. How has their immune system evolved to shield them from these pathogens?
Nov 28, 2022
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Remnants of ancient viruses in the human genome are active in healthy tissues as well as diseased ones, limiting their utility as disease biomarkers, according to a study by Aidan Burn at Tufts University in Boston, U.S. ...
Oct 18, 2022
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Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15% in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine ...
Jul 21, 2022
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When Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, infects a person, the body's immune response is critical to how the disease will progress—either helping the body fight the bacterium or exacerbating ...
Jul 29, 2021
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Each pathogen relies on a unique set of strategies and surface & secreted molecules that enable it to colonize and infect host cells, which are collectively known as "virulence factors."
May 20, 2021
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Severe symptoms of COVID-19, leading often to death, are thought to result from the patient's own acute immune response rather than from damage inflicted directly by the virus. Immense research efforts are therefore invested ...
May 12, 2021
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