Biomedical engineers at Duke University have demonstrated the most effective treatment for pancreatic cancer ever recorded in mouse models. While most mouse trials consider simply halting growth a success, the new treatment ...
Oct 20, 2022
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A Japanese research team has successfully developed a system to predict the severity of Alport syndrome, a serious hereditary kidney disease that occurs in about 1 out of 5,000 people in the US. Patients with Alport syndrome ...
Apr 6, 2020
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A researcher from the University of Houston has created a form of recombinant insulin that could potentially address some of the biggest concerns about the lifesaving drug, including its price.
May 15, 2019
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Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material ...
Dec 26, 2016
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People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells.
Jul 19, 2014
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A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally ...
Jul 14, 2013
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A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta Αβ plaques that are associated with ...
Jun 27, 2013
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A team of German and Italian EU-funded scientists has designed peptides that can target the protein-protein interface of an enzyme that plays a key part in the DNA synthesis crucial for cancer growth.
Aug 8, 2011
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Peptides (from the Greek πεπτός, "digested" from πέσσειν "to digest") are short polymers of amino acid monomers linked by peptide bonds. They are distinguished from proteins on the basis of size, typically containing less than 50 monomer units. The shortest peptides are dipeptides, consisting of two amino acids joined by a single peptide bond. There are also tripeptides, tetrapeptides, etc. Amino acids which have been incorporated into a peptide are termed "residues"; every peptide has a N-terminus and C-terminus residue on the ends of the peptide (except for cyclic peptides). A polypeptide is a long, continuous, and unbranched peptide. Proteins consist of one or more polypeptides arranged in a biologically functional way and are often bound to cofactors, or other proteins.
The size boundaries which distinguish peptides, polypeptides, and proteins are arbitrary. Long peptides such as amyloid beta can be considered proteins, whereas small proteins such as insulin can be considered peptides.
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