The fibroblast growth factor 19 (FGF19) engineered analogue, NGM282, inhibits bile acid synthesis, decreases markers of hepatic inflammation, and significantly improves markers of fibrosis in patients with primary sclerosing ...
Apr 13, 2018
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A large register-based study conducted in Sweden has found that statins are associated with a markedly reduced risk of all-cause mortality, liver transplantation, liver cancer, and variceal bleeding in patients with primary ...
Apr 12, 2018
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(HealthDay)—Fecal microbiota transplantation (FMT) from a rationally selected donor seems safe and effective for patients with primary sclerosing cholangitis (PSC), according to a study presented at the World Congress of ...
Oct 16, 2017
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Primary sclerosing cholangitis is a currently incurable liver disorder, primarily affecting younger adults aged between 30 and 40. A European multi-centre Phase II study led by MedUni Vienna in close collaboration with MedUni ...
Jun 13, 2017
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(HealthDay)—Fluorescence in situ hybridization (FISH) is associated with increased sensitivity compared with brush cytology for diagnosing cholangiocarcinoma in indeterminate biliary strictures, according to a study published ...
Jun 9, 2017
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Primary Sclerosing Cholangitis (PSC) is a debilitating rare disease of the liver with no effective treatment. Reported in Nature Genetics researchers from the Wellcome Trust Sanger Institute, Mayo Clinic and their collaborators ...
Dec 19, 2016
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An article published today in the New England Journal of Medicine updates the medical community on a potentially devastating liver disease that afflicts approximately 29,000 Americans. Primary sclerosing cholangitis, or PSC, ...
Sep 22, 2016
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An international research collaboration has identified bacteria in the bile duct as a potential risk factor in the development of bile duct cancer, or Cholangiocarcinoma (CCA), a rare but aggressive form of cancer with symptoms ...
Jun 24, 2016
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A new study presented today provides hope for a new treatment in patients with primary sclerosing cholangitis, a rare condition characterised by inflammation and scarring in the bile ducts of the liver and for which there ...
Apr 16, 2016
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A global study involving 50 different research centres has found hundreds of genes which cause five common, hard-to-treat and debilitating inflammatory diseases, paving the way to new treatments for these conditions.
Mar 15, 2016
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