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Immunology news
Oncology & Cancer
Biomarkers identified for successful treatment of bone marrow tumors
CAR T cell therapy has proven effective in treating various hematological cancers. However, not all patients respond equally well to treatment. In a clinical study, researchers from the University of Leipzig Medical Center ...
9 hours ago
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How the immune system learns from harmless particles
Our lungs are bombarded by all manner of different particles every single day. While some are perfectly safe for us, others—known as pathogens—have the potential to make us ill. The immune system trains its response whenever ...
9 hours ago
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Researchers find pregnancy cytokine levels impact fetal brain development and offspring behavior
Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric ...
6 hours ago
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Experts develop immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease. ...
2 hours ago
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Identifying a new liver defender: The role of resident macrophages
Osaka University researchers have discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier ...
Apr 25, 2024
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How immune cells communicate to fight viruses: New mouse model enables identification of chemokine producers and sensors
Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells.
Apr 25, 2024
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CD7 CAR T-cell therapy, stem-cell transplant beneficial for CD7-positive tumors
For patients with relapsed or refractory CD7-positive leukemia or lymphoma, sequential CD7 chimeric antigen receptor (CAR) T-cell therapy followed by haploidentical hematopoietic stem-cell transplantation (HSCT) is safe and ...
Apr 25, 2024
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Scientists team up to expand vaccine science's role in the fight against MRSA and other infections
Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments. It's estimated that antimicrobial-resistant infections killed more than 1 million people worldwide in 2019, ...
Apr 24, 2024
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Newly discovered mechanism helps tumor cells evade the immune system early on
Tumors actively prevent the formation of immune responses by cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München ...
Apr 24, 2024
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Immune cells on standby are constantly stimulated by healthy tissue, new study finds
When pathogens invade the body, the immune system must react immediately to prevent or contain an infection. But how do our defense cells stay ready when no attacker is in sight?
Apr 24, 2024
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CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in clinical trial
Researchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist have published results of a Phase I clinical trial of a ...
Apr 24, 2024
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Unveiling immune features of heart failure paves the way for targeted therapies
In a recent study published in the Science Bulletin, researchers comprehensively examined the composition and phenotypic features of myeloid cells in human failing hearts at a single-cell level, offering valuable insights ...
Apr 24, 2024
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Allergies can make you miserable. Here's how to track pollen levels near you
Allergy season can bring misery to tens of millions of Americans each year.
Apr 24, 2024
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Researchers identify a cause of immunodeficiency after stroke and heart attack
Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack. These patients suffer immune disturbances and are very frequently susceptible to life-threatening bacterial infections. Until ...
Apr 23, 2024
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How B cells recognize new variants of SARS-CoV-2
B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen.
Apr 23, 2024
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Swimming short fibrous nasal drops achieve intraventricular administration
Adequate drug delivery across the blood-brain barrier is a critical factor in treating central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of the nasal cavity, Prof. Cui is the first to ...
Apr 23, 2024
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Bacteria in the intestine that change in response to inflammation could have an impact on our immune system
Gut bacteria have emerged as a focal point of scientific exploration, with their intricate roles in our metabolism, nutrition, and overall health coming into sharp focus. New research from the Technion—Israel Institute ...
Apr 22, 2024
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Improving cancer immunotherapy by prolonging T-cell survival
In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...
Apr 22, 2024
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Hitchhiking of synthetic antigen stimulates antibody production against cancer cells
Researchers at the Indian Institute of Science (IISc) have designed a synthetic compound (antigen) that can latch on to a protein in blood and hitchhike a ride to the lymph node, where it can boost the production of antibodies ...
Apr 22, 2024
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