inflammatory protein research offers treatment strategies for a rare, potentially fatal lung disease
Most of the time, our immune systems do a great job defending against infection and keeping our bodies running smoothly. Sometimes, though, our immune system actually makes things worse. Case in point—researchers from Japan ...
5 hours ago
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Researchers find that a new mother's immune status varies with her feeding strategy
In one of the first studies of its kind, UC Santa Barbara researchers have found that the immune status of postpartum mothers shifts with how she feeds her baby. According to a paper published in the journal Scientific Reports, ...
7 hours ago
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
Intestinal epithelial cells line the inner wall of the gut, creating a barrier against dangerous bacteria like enteropathogenic E. coli that seek to attach to and destroy this barrier. Such pathogens pose significant risks ...
May 7, 2024
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Researchers suggest B-cells may play role in lung transplant rejection
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation, which can lead to rejection, according to a study published in the Journal of Clinical Investigation.
May 7, 2024
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Years after his death, late scientist's work could yield new cancer treatments
Some of the final work of a late University of Virginia School of Medicine scientist has opened the door for life-saving new treatments for solid cancer tumors, including breast cancer, lung cancer and melanoma.
May 7, 2024
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Ion channel discovery offers hope for long COVID patients
Researchers from Griffith University's National Center for Neuroimmunology and Emerging Diseases (NCNED) have made a discovery that could bring relief to those struggling with long COVID.
May 7, 2024
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Researchers make strides in understanding little-known autoimmune myelin-impairing disorder
Blindness and paralysis are often the devastating consequences of little-known disease myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). An Australian research collaboration is looking to change this, ...
May 7, 2024
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Gut bacteria metabolite shows promise in fighting inflammatory bowel disease
Gut microbiota or the population of microbial inhabitants in the intestine, plays a key role in digestion and maintenance of overall health. Any disturbance in the gut microbiota can, therefore, have a systemic impact. Intestinal ...
May 7, 2024
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You're probably not allergic to penicillin, even if you think you are
If you're one of the millions of Americans who have a penicillin allergy listed on your medical record, research suggests it's highly likely that this label is inaccurate.
May 7, 2024
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Biomolecular atlas for bone marrow offers unprecedented window into blood production
Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have revealed a powerful new bone marrow atlas that will offer the public a first-of-its-kind ...
May 6, 2024
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Study uncovers at least one cause of roadblocks to cancer immunotherapy
T cells—the body's foot soldiers against invaders, ranging from everyday infections to cancers—are integral to many successful immunotherapies. However, a frustrating factor is that immunotherapies do not always work.
May 6, 2024
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Vagus nerve activation of the spleen shows promise to treat infections
One of the main roles of the spleen is to help the body's immune system fight infections. The spleen does this through producing and regulating antibodies—antibody production is negatively affected in various conditions, ...
May 6, 2024
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Study provides a blueprint of tumor-infiltrating B cells with therapeutic implications
In a study published in Science on May 3, researchers unveiled two responding patterns of tumor-infiltrating B cells with therapeutic implications.
May 6, 2024
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Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptoms
B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), disproving the previous consensus that T cells ...
May 6, 2024
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Researchers generate direct measurement of interaction between immune cells and cancer cells from a patient's biopsy
Researchers at Bar-Ilan University have unveiled a technology that promises to improve cancer treatment decisions based on a patient's biopsy. The pioneering biological research and development measures changes in immune ...
May 6, 2024
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Scientists discover new immunosuppressive mechanism in brain cancer
The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...
May 3, 2024
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Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T–cell immunotherapy, where a patient's own immune cells are re-engineered to attack cancer ...
May 3, 2024
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Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies
Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions.
May 3, 2024
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